Make the seasoned butter: Combine the softened butter, olive oil, salt, garlic powder, Italian seasoning, and black pepper in a small bowl.
Prepare the oven: Preheat the oven to 350°F. Lightly grease a standard muffin tin or eight individual foil cups.
Shape the biscuit crusts: Separate the biscuits and press one into each muffin cup, working the dough across the bottom and up the sides. Prick the bottoms and sides several times with a fork.
Add the sauce: Brush the inside of each biscuit cup with the seasoned butter, then spread about ½ heaping teaspoon of pizza sauce inside.
Fill the cups: Add a heaping tablespoon of mozzarella and about ½ tablespoon of chopped pepperoni to each cup. Repeat the cheese and pepperoni layers, then sprinkle with a little Italian seasoning if desired.
Bake: Place the muffin tin in the oven and bake for 20–23 minutes, or until the biscuit edges are golden brown and the cheese is melted.
Cool and serve: Let the mini pot pies cool for a few minutes, then carefully remove them from the pan and serve warm.